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A study shows the "noticeable" effects of grape consumption on health and age


 A study shows the "noticeable" effects of grape consumption on health and age


A study reported that the long-term addition of grapes to the rat diet led to unique gene expression patterns, reduced fatty liver and prolonged life of high-fat Western-style animals


Research team leader Dr. John Pizzotto of Western New England University said he was particularly surprised by these findings, adding: 


"We've all heard the saying 'what you eat is you'

which is obviously true because we all start as fetuses

and end up becoming adults by eating.


But these studies add a whole new dimension to this old saying, Not only is food transformed into parts of our bodies, but as evidenced by our work with food grapes, it actually changes our genetic expression, and that's really cool. "


What is the effect of this change in gene expression?


  • According to the paper
  • fatty liver is prevented or delayed
  • and fatty liver is a condition that affects about 25% of
  • the world's population and can eventually lead to undesirable effects

  • including liver cancer.


According to a recent study published by a collaborative team led by Dr. Jeffrey Idle in the journal Food & Function, the genes responsible for fatty liver growth are changed in a useful way by eating grapes, in overtime, the expression of genes is not only changed

but metabolism is also changed by nutritional grapes.


The research found that grape-fortified diets increase levels of antioxidant genes. According to Pizzotto:


 "Many people think about taking supplements that are high in antioxidants.


In fact :

  • you cannot consume enough antioxidants to make a big difference

  • but if you change the level of antioxidant gene expression
  • as we noted with the addition of grapes to the diet

  • the result is a catalytic response that can make a real difference. "


Another notable effect illustrated in this research is

the ability of grapes to prolong the life of mice when following a high-fat Western diet. 


Western high-fat diet is associated

with adverse conditions such as obesity


  1. cardiovascular disease
  2. diabetes, autoimmune disease
  3. cancer and Alzheimer's disease.


Adding grapes to the diet not only affects the rate of consumption

or body weight but delays natural death

although the translation of years of life from mouse to human is not an accurate science, and Pizzotto notes that his best estimate is that the change observed in the study will correspond to an additional 4-5 years in human life.


The study noted that grape consumption

altered gene expression in the brain


while grape consumption had positive effects on cognition, and perception that was weakened by a high-fat diet, suggesting that changing gene expression was what produced such a useful response.